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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1997 2
1998 2
1999 1
2000 2
2001 1
2002 1
2006 1
2008 3
2009 4
2010 3
2011 10
2012 14
2013 4
2014 11
2015 6
2016 4
2017 4
2018 4
2019 2
2020 4
2021 3
2023 2
2024 1

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80 results

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Page 1
Regulating T-cell differentiation through the polyamine spermidine.
Carriche GM, Almeida L, Stüve P, Velasquez L, Dhillon-LaBrooy A, Roy U, Lindenberg M, Strowig T, Plaza-Sirvent C, Schmitz I, Lochner M, Simon AK, Sparwasser T. Carriche GM, et al. J Allergy Clin Immunol. 2021 Jan;147(1):335-348.e11. doi: 10.1016/j.jaci.2020.04.037. Epub 2020 May 11. J Allergy Clin Immunol. 2021. PMID: 32407834 Free article.
Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.
Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. Divakaruni AS, et al. Cell Metab. 2018 Sep 4;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043752 Free PMC article.
C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function.
Wang Y, Dembowsky K, Chevalier E, Stüve P, Korf-Klingebiel M, Lochner M, Napp LC, Frank H, Brinkmann E, Kanwischer A, Bauersachs J, Gyöngyösi M, Sparwasser T, Wollert KC. Wang Y, et al. Circulation. 2019 Apr 9;139(15):1798-1812. doi: 10.1161/CIRCULATIONAHA.118.036053. Circulation. 2019. PMID: 30696265 Free PMC article.
BACKGROUND: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Inflammatory cell trafficking after MI is controlled by C-X-C motif chemokine ligand 12 (CXCL12) and its receptor, C-X-C …
BACKGROUND: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Infl …
A clinically-relevant STING agonist restrains human TH17 cell inflammatory profile.
Damasceno LEA, Cunha TM, Cunha FQ, Sparwasser T, Alves-Filho JC. Damasceno LEA, et al. Int Immunopharmacol. 2023 Nov;124(Pt B):111007. doi: 10.1016/j.intimp.2023.111007. Epub 2023 Sep 29. Int Immunopharmacol. 2023. PMID: 37778170
In this line, STING was found to limit murine T(H)17 pro-inflammatory program in vitro. Here we demonstrate that 2'3'-c-di-AM(PS)(2)(Rp,Rp), a STING agonist that has been undergoing clinical trials for antitumor immunotherapy, activates the STING signalosome in differentia …
In this line, STING was found to limit murine T(H)17 pro-inflammatory program in vitro. Here we demonstrate that 2'3'-c-di-AM(PS)(2)( …
Inhibition of Mitochondrial Translation Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation by Targeting Vγ4+ γδ T Cells.
Dhillon-LaBrooy A, Braband KL, Tantawy E, Rampoldi F, Kao YS, Boukhallouk F, Velasquez LN, Mamareli P, Silva L, Damasceno LEA, Weidenthaler-Barth B, Berod L, Almeida L, Sparwasser T. Dhillon-LaBrooy A, et al. J Invest Dermatol. 2024 Apr;144(4):844-854.e2. doi: 10.1016/j.jid.2023.09.275. Epub 2023 Oct 12. J Invest Dermatol. 2024. PMID: 37832844
The antibiotic linezolid, which blocks mitochondrial translation, inhibited the production of mitochondrial-encoded protein cytochrome c oxidase in Vgamma4(+) gammadelta T cells and systemically reduced the frequencies of IL-17A(+) Vgamma4(+) gammadelta T cells, effectivel …
The antibiotic linezolid, which blocks mitochondrial translation, inhibited the production of mitochondrial-encoded protein cytochrome c …
Sandwich Immunoassay for Bioactive Plasma Adrenomedullin.
Weber J, Sachse J, Bergmann S, Sparwaßer A, Struck J, Bergmann A. Weber J, et al. J Appl Lab Med. 2017 Sep 1;2(2):222-233. doi: 10.1373/jalm.2017.023655. J Appl Lab Med. 2017. PMID: 32630976 Free article.
Reliable methods for the simple quantification of bioactive ADM (bio-ADM) are lacking. METHODS: Monoclonal antibodies against the amidated C-terminus and middle portion of bio-ADM were generated and used for the development of a 1-step immunometric assay for the specific q …
Reliable methods for the simple quantification of bioactive ADM (bio-ADM) are lacking. METHODS: Monoclonal antibodies against the amidated …
Foxp3+ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.
Blankenhaus B, Reitz M, Brenz Y, Eschbach ML, Hartmann W, Haben I, Sparwasser T, Huehn J, Kühl A, Feyerabend TB, Rodewald HR, Breloer M. Blankenhaus B, et al. PLoS Pathog. 2014 Feb 6;10(2):e1003913. doi: 10.1371/journal.ppat.1003913. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516385 Free PMC article.
Strikingly, Treg depletion reduced parasite burden selectively in BALB/c but not in C57BL/6 mice. Treg function was apparent in both strains as Treg depletion increased nematode-specific humoral and cellular Th2 response in BALB/c and C57BL/6 mice to the same extent …
Strikingly, Treg depletion reduced parasite burden selectively in BALB/c but not in C57BL/6 mice. Treg function was apparent in both …
Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium.
Wang Z, Friedrich C, Hagemann SC, Korte WH, Goharani N, Cording S, Eberl G, Sparwasser T, Lochner M. Wang Z, et al. Mucosal Immunol. 2014 Nov;7(6):1290-301. doi: 10.1038/mi.2014.17. Epub 2014 Mar 19. Mucosal Immunol. 2014. PMID: 24646939 Free article.
In this project, we therefore studied the impact of Foxp3(+) regulatory T cells (Treg) on the infectious and inflammatory processes elicited by the bacterial pathogen C. rodentium. Surprisingly, we found that depletion of Treg by diphtheria toxin in the Foxp3(DTR) (DEREG) …
In this project, we therefore studied the impact of Foxp3(+) regulatory T cells (Treg) on the infectious and inflammatory processes elicited …
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
Almeida L, Dhillon-LaBrooy A, Castro CN, Adossa N, Carriche GM, Guderian M, Lippens S, Dennerlein S, Hesse C, Lambrecht BN, Berod L, Schauser L, Blazar BR, Kalesse M, Müller R, Moita LF, Sparwasser T. Almeida L, et al. Immunity. 2021 Jan 12;54(1):68-83.e6. doi: 10.1016/j.immuni.2020.11.001. Epub 2020 Nov 24. Immunity. 2021. PMID: 33238133 Free PMC article.
80 results